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Mixing Kratom with Other Prescription Drugs is Dangerous

Mixing Kratom with Other Prescription Drugs is Dangerous

Many Southeast Asian communities use Kratom as an alternative medicine. Its popularity in other continents has increased over the years. Kratom is used to treat anxiety disorders, opioid addiction and to relieve chronic pain. But, many countries lack laws that regulate Kratom use. Here is an insight into the pharmacology of Kratom and why it is dangerous to mix it with prescription drugs.

The Pharmacology of Kratom

The Food and Drug Administration (FDA) published a report in February 2018 which revealed that Kratom is an opioid. The agency identified over 20 alkaloids such as indole alkaloid mitragynine which is a kappa-opioid receptor agonist. It is more powerful than morphine. Scientific research shows that mitragynine acts on the delta and mu-opioid receptors, noradrenergic and serotonergic pathways. It stimulates the alpha-2 adrenergic receptors and blocks the 5-hydroxytryptamine 2A receptors.

Kratom’s Interaction with other Medications

Here are some interactions between Kratom and prescription drugs that can be fatal:

1. Psychedelics and Kratom

Psychedelics are a form of medication that causes psychedelic experiences. They are serotonin receptor agonists. Psychedelics include psilocybin, mescaline, and LSD. It is not wise to combine them with Kratom.

2. Stimulants and Kratom

Coffee and cocaine are the most popular stimulants worldwide. However, amphetamines and yohimbine are stimulant drugs. Kratom is a natural stimulant. So, you might get overstimulated if you combine it with other stimulants. It will cause serious side effects such as anxiety, agitation, excessive sweating, and heart palpitations.

A combination of Kratom and other stimulants can cause high blood pressure. You should observe your seizure threshold. Experienced users of Kratom products combine it with little coffee.

3. Depressants and Kratom

There are different types of depressants. They include anti-anxiety medications, tranquilizers, and benzodiazepines. The drugs work in the same way as opiates. You will experience severe sedation if you combine depressants with Kratom. It could result in respiratory depression. Avoid brewing kava since it is a mild depressant.

4. Selective Serotonin Reuptake Inhibitors (SSRIs) and Kratom

Doctors use SSRIs to treat severe depression. They are known as anti-depressants. Kratom interacts with the mu-receptors while SSRI interacts with serotonin receptors in your brain. At times, both receptors interact with one another in specific processes. Thus, Kratom and SSRIs might react and damage your brain.

5. Monoamine Oxidase Inhibitors (MAOIs) and Kratom                                                                          

Monoamine Oxidase Inhibitors breakdown monoamine compounds. They prevent monoamine oxidases from metabolizing food in your stomach. It is risky to combine Kratom with MAOIs as it might cause fatal side effects. Avoid foods that are rich in amino acid tyramine as they usually inhibit monoamine oxidases.

Don’t combine Kratom with bay bean, sea bean, Syrian rue, and passionflower since they are Monoamine Oxidase Inhibitors. Combining Kratom with herbs or foods with a high amino acid tyramine content will stimulate you beyond the standard threshold. You might experience mental block and anxiety disorders.

The Drug Enforcement Administration (DEA) doesn’t control Kratom use in the United States. Various states have different regulation which controls the use and possession of Kratom. You can take Kratom in the form of capsules or extracts. It is advisable to take small doses to relieve mild pain. Also, don’t mix Kratom with prescription drugs such as psychedelics, depressants and Monoamine Oxidase Inhibitors (MAOIs).

Kratom is indeed a powerful plant. When used properly it can bring you overall wellness.

Does Kratom Cure Addiction?

Does Kratom Cure Addiction?

Kratom is an herbaceous plant whose leave contains 7-α-hydroxy mitragynine and mitragynine. It is popular in South East Asia. Health facilities offer Kratom as a cure for different health conditions. You can consume it as pills, powder and an extract. Some states in the U.S. ban the use and sale of Kratom. In this post, we discuss whether Kratom is capable to cure addiction.

Case Presentation

Courtney True is a 41-year-old woman who grew up in Mississippi. She got addicted to opioids at a tender age of 14. The addictions started after a doctor gave Courtney a Percocet prescription for chronic migraines. She got hooked to OxyContin by the time she reached 24. Ten years later, True relocated to Maine and became a nurse. She got married and bore two children. The Maine nurse started using heroin after the Drug Enforcement Administration (DEA) traced illegal online pharmacies.

True tried to quit abusing heroin many times. She used various remedies for withdrawal symptoms including valerian root and Imodium A-D. The young mother found a Kratom thread in Reddit in December 2016. Then, she had refrained from taking heroin for two days. Courtney suffered from diarrhea, cold sweats, and stomach cramps. She didn’t know much about the different Kratom forms and strains. But True was willing to try Kratom cure for her opioid addiction.

She asked her husband, John Wolstenhulme, to take her to a smoke shop in Portland to buy Kratom capsules, extracts, and leaves. They cost her $100. Courtney swallowed several capsules when she got inside their family car. Her withdrawal symptoms faded within 20 minutes. She hasn’t taken heroin for the last 17 months.

Courtney takes several glasses of grapefruit-Kratom juice daily. She recently confessed that Kratom has saved her family. For instance, Jeff Wolstenhulme, True’s stepson used fentanyl while John used opioids for 20 years. They have refrained from taking narcotics for more than three months now. Also, Courtney urged her mother to take Kratom to treat irritable bowel syndrome.

Kratom’s Ability to Cure Opioid Addiction

About 11 percent of essential drugs are obtained from plants, according to the World Health Organization. Drug enforcement agencies such as the Food and Drug Administration (FDA) and the DEA have debated on whether Kratom is an opioid. Oliver Grundmann from the University Of Florida College Of Pharmacy has published several reviews on the chemical compounds and structure of Kratom.

Medical facilities have provided medication-assisted treatments and methadone to opioid addicts for long. Even so, methadone is a strong opioid which you can get addicted to. The FDA requires all rehabs to administer methadone in small quantities. Kratom evokes euphoria when you take it in moderate doses. Avoid using it for more than six months to avoid Kratom addiction. Prolonged use of the extract causes opioid craving. Physicians treat it with naloxone and buprenorphine.

Kratom cure is a powerful pain reliever and sedative. You can consume Kratom in different forms including capsule, extract, and pill. Some rehabilitation centers use it to treat opioid withdrawal symptoms. Kratom interacts with the opioid receptors in your brain hence reducing the urge to take drugs. It is advisable to take Kratom in small doses as it causes sedation when taken in large quantities. Despite being ruled out by FDA and DEA as having an opioid effect to its users, Kratom does have its share of positive effects. There are more ways in which you can use this plant as medicine. Read our guides at https://www.apexkratom.com to learn more.

Where is Kratom Legal in the United States?

Where is Kratom Legal in the United States?

Kratom is an evergreen tree that is common in Southeast Asia. Its botanical name is Mitragyna speciosa. Many people use it as an herbal supplement. It has opioid and psychoactive properties. You can consume it as capsules, gum or tablets. But, many consumers have a murky understanding of kratom’s legality in the United States. Read on to learn more about it.

Is Kratom Legal in the United States?

The U.S. has a complicated legal system. It has State level and Federal legal system which use different legislations. Many American enforcement agencies make it hard for many people to understand the legality of kratom in the country. Consumers pay penalties and fines when they use kratom in certain states. Yet, American citizens have been using kratom for over twenty years. Some health authorities don’t believe that it is safe for consumption.

The Food and Drug Administration (FDA) recorded several deaths between 2005 and 2015 which resulted from kratom use. It confiscated kratom products that were contaminated. The U.S Army banned soldiers from using the herbal supplement. Alabama, Arkansas, Wisconsin, Vermont, and Indiana banned it. Many people imported kratom in America between 2010 and 2016, according to the International Narcotics Control Board. The Drug Enforcement Authority (DEA) classified it as being unfit for consumption.

Some legislators and consumers protested in many states and asked them to delegalize kratom. The U.S. has several regulations that control the consumption and purchase of kratom. Although the federal level law is general, different states use unique legal systems. The following states have clear kratom regulations:

  1. California: Kratom use is legalized in all counties apart from San Diego
  • Florida: Kratom is only illegal in Sarasota County
  • Illinois: Kratom is illegal in Jerseyville and in people who are below 18 years
  • Alabama: Kratom is a Schedule 1 controlled product
  • Tennessee and Arkansas: Kratom use is illegal
  • Indiana: Kratom is an illegal synthetic substance
  • Wisconsin: Kratom is a Schedule 1 drug

DEA has raised many concerns about the legality of kratom. Some health groups are urging the federal government to make kratom illegal in all states while other people believe that it is an effective treatment for opioid addiction. The Drug Enforcement Agency wanted to list kratom in the Schedule 1 category in 2016. It claimed that the herb has opiate effects that are like those of cocaine, ecstasy, LSD, and heroin. Even so, the DEA proposition didn’t go through.

The Legal Status of Kratom in America

Further research is essential to determine the benefits of kratom. It acts on the brain receptors of consumers thus alleviating mild and chronic pain. The U.S. Army prohibits all soldiers from using kratom. The FDA sent a warning to pharmaceutical firms that sold unapproved kratom products in March 2018. Be vigilant to kratom regulations in your state to avoid paying penalties and fines.

Kratom use, possession, and sale are illegal in:

  • Arkansas
  • Alabama
  • Indiana
  • Vermont
  • Tennessee
  • Wisconsin

Kratom is popular for its anesthetic and sedative effects. Although it is native to Southeast Asia, people from other countries grow kratom. It is advisable to use the right kratom dosage. Some people use it to relieve chronic pain. American states such as Alabama, Arkansas, Indiana, Tennessee, Vermont, and Wisconsin prohibit the consumption and sale of kratom.

Reference:

https://www.ridgefieldrecovery.com/drugs/kratom/related/legality-of-kratom/
Distinctive Effects of the Green Maeng Da Kratom

Distinctive Effects of the Green Maeng Da Kratom

Kratom is an herbaceous plant which is mostly found in Asia. It is common in Thailand and Bali. Many people use kratom for different purposes. Some users take different products for fun while others use them to treat certain health conditions. There are different strains such as Bali, Maeng Da Thai, and Sumatra. Read on to learn the health effects of Green Maeng Da kratom and its right dosage.

6 Health Effects of Green Maeng Da Kratom:

Maeng Da doesn’t cause a hyperactive sensation which is often associated with other kratom strains. Here are some of its effects:

1. Pain Relief

Maeng Da has different pain-relieving abilities from those of Red Vein Bali. It is a mild pain reliever. You can use it to alleviate chronic back pain.

2. Mind Clearance

Research reveals many people struggle to focus on a particular issue. Maeng Da clears your mind hence helping you perform better at work or in school. It is appropriate for people who are anxious and who are apprehensive.

3. Better Socialization

Most introverts avoid interacting with people in large gatherings. Some of them lack the courage to approach and start conversations with strangers. A small dosage of Maeng Da can significantly reduce social anxiety in a consumer. It makes you more talkative and bold. Green kratom helps you build and maintain long-term friendships and relationships. Besides, you can combine it with alcohol at dinner parties.

4. High Self Confidence

People who have low confidence are often unable to deliver speeches before a huge audience. Take Maeng Da if you are shy. It will boost your confidence and help you express your emotions and opinions to family and friends.

5. Anti-depressant

White kratom strains are powerful energy boosters. Some people get hyperactive when they take them. It worsens their depression. Physicians recommend taking green kratom to treat depression. It increases apathy and lethargy. Green Maeng Da is suitable for people with severe anxiety and depression.

6. Energy Boost

Maeng Da improves your focus, concentration, and productivity. It is a great energy booster which you should take early in the morning. Avoid consuming Maeng Da before you go to bed at night as it might disrupt your sleep pattern.

The Right Dosage for Maeng Da Kratom

Maeng Da kratom is rich in alkaloids. It provides distinctive effects when you consume it in small dosages. A high-quality kratom capsule contains up to 5g of kratom powder. You can experience more health effects when you take a 2g kratom strain. Maeng Da is a powerful tranquilizer when you take it in high dosage. However, Maeng Da is a moderate kratom strain. Beginners can start taking 2g of kratom powder while average users consume 5g of Maeng Da to achieve different effects. Green Maeng Da is a powerful kratom strain with energizing effects. It is suitable for people suffering from anxiety, depression, low self-esteem, and memory loss. It is wise to purchase kratom from licensed dealers who often test their products. Take a low dosage of Maeng Da since it has sedative effects when consumed in high quantities.

Taking Kratom While Pregnant

Taking Kratom While Pregnant

Pregnancy is a sensitive period in every woman’s life. It is important to check your diet and medication. Avoid taking over-the-counter drugs and prescription medication. Many expectant women prefer taking alternative medicine. Some of them consume different kratom products. Yet, they aren’t aware of whether they are safe. Here is an insight into kratom safety during pregnancy.

Kratom has an Unclear Mechanism

Kratom has over 40 alkaloids. Different strains have varying alkaloid ratios. It is tricky to determine which kratom components cause certain effects, according to Jay McLaughlin. Further research is necessary to determine the effects of 7-hydroxy mitragynine and alkaloids mitragynine.

Mitragynine produces analgesia. It activates the μ opioid receptor thus relieving mild and chronic pain. Different kratom elements have special action mechanisms. They have distinctive effects. Kratom acts as an energy booster when you take in in low doses. It has analgesic effects when you consume it in large quantities.

Kratom Contamination

Contaminated kratom products cause disease outbreaks in many regions, according to the Centers for Disease Control (CDC). Some dealers aren’t concerned about kratom safety. They don’t maintain high hygiene while processing and packing kratom. Bacterial infections pose a great risk to expectant women. They adversely affect unborn babies. There is a high number of contaminated products since there are different sources of kratom.

Kratom Creates Analgesia and Euphoria

Kratom interacts with the opioid receptors thus making it an effective treatment for opioid addiction. It creates analgesia in all consumers. But, it doesn’t depress respiration, unlike morphine. Many women don’t inform health professionals about their kratom use. It can be confirmed by conducting urine tests.

Withdrawal in Babies

Expectant mothers who take moderate and high doses of kratom expose their unborn babies to kratom’s effects. Newborns who have been exposed to kratom use display opiate withdrawal signs such as prolonged crying, low appetite, and constant sneezing. A standard urine toxicology screen might not detect the amount of kratom in a mother’s bloodstream.

Doctors administer morphine to newborns who suffer from opiate withdrawal. Mothers should wean off babies slowly until all symptoms dissipate. Physicians should closely watch them for two days before they discharge them.

Mothers are aware of the side effects of taking opioid drugs during pregnancy. Some of them believe that kratom is a safe treatment for opioid withdrawal. Even so, most of them have a murky understanding of how kratom interacts with brain receptors.

Does Kratom Use Cause Congenital Disorders?

Few studies have been conducted to determine the effect of kratom in fetuses. It distorts the formation of their brain receptors. Expectant mothers should avoid taking any kratom product. The Food and Drug Administration (FDA) doesn’t regulate. Thus, kratom’s safety isn’t guaranteed. Recent research reveals that opioids are dangerous during pregnancy. Some of them cause birth defects and miscarriages. Consult a health professional about kratom safety before you start taking it. It might cause withdrawal symptoms when you stop taking it. Furthermore, kratom is a powerful allure. You might get addicted to it if you take high dosages.